Weight Loss / Metabolic
Semaglutide
⭐ PopularGLP-1 receptor agonist. Active ingredient in Ozempic and Wegovy. ~15% average weight reduction.
✅ Potential Benefits
- ~15% average body weight reduction (STEP trials)
- Significant appetite suppression
- Cardiovascular risk reduction (SELECT trial)
- Blood sugar and HbA1c control
- Weekly injection — convenient dosing
💊 Dosing Protocol
Start 0.25mg/week SubQ x4 weeks → 0.5mg → 1mg → 1.7mg → 2.4mg max (weight loss protocol).
⏱ Half-Life
~7 days
⚠️ Common Side Effects
Nausea, vomiting, diarrhea, constipation. Fatigue, headache, injection site reactions.
🚫 Warnings & Contraindications
- Contraindicated in personal/family history of MEN2 or medullary thyroid carcinoma
- Pancreatitis risk — monitor for severe abdominal pain
- Do not use in pregnancy
- Diabetic retinopathy complications reported
- Risk of hypoglycemia when combined with other glucose-lowering agents
🚨 Adverse Effects
Acute pancreatitis, gallbladder disease, acute kidney injury (secondary to dehydration), suicidal ideation (rare, under investigation).
📬 Interested in Semaglutide?
Have questions about this peptide or want to discuss availability?
✉️ Send an Inquiry⚕️ This information is for educational purposes only and does not constitute medical advice. Always consult a licensed healthcare provider before beginning any wellness protocol.
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